The Senior Medical Affairs Director Neurology will provide strategic leadership to Alexion’s neurology portfolio and to our expanding neurology pipeline portfolio. Responsible for providing strong scientific and medical expertise with an in-depth understanding of neuro-immunology and complement mediated diseases in neurology. The SD will contribute to the development and implementation of the strategic plans for multiple compounds and indications in a strongly matrixed environment with effective cross-functional collaboration. The SD will work with the rest of Alexion’s Global Medical Affairs to maximize patients’ outcomes by setting and continuously advancing the evidence-based medical standard of care.
Job Duties & Responsibilities
Develop and implement global medical strategies and plans as well as the strategically aligned tactical plan (also responsible for the execution) for the respective assets/indications. Will work cross-functionally as well as closely with the regions and countries to transform medical practice. Responsible for the following:
- Medical representation at the relevant Global Product Teams (GPTs)
- Serve as the Medical Affairs medical expert for the cross functional group
- Contribute to the development of the target product profiles (TPPs)
- Support the other representing functions on the key activities as applicable
- Lead on the situational assessment and the global product strategy development including harmonization of activities involving KOLs:
- Develop in-year global medical strategy, Implementation and budget plan for global initiatives as applicable
- Development and execution of major registration LCM program and geographically expansion strategy
- Provide medical review and ensure alignment strategy of Investigator sponsored research (ISR) proposals including the review of the Final Report
- Provide clear strategic guidance to scientific communication, internal medical training, external medical education (CME, Symposia, medical education), Medical info, in developing functional plans supporting global medical strategy
- Serves as the medical expert and resource within ALXN in support of the therapeutic area
- Lead content development and presentation for external medical education programs, and other Global Medical initiatives
- Develop, conduct, or participate in therapeutic training programs for Alexion personnel.
- Medical affairs review of field medical tools, internal commercial training material
- Medical affairs review of value proposition
- Medical affairs review of congress abstracts and publications
- Establishes strategic partnerships with centers of excellence and KOLs in areas of scientific interest and serves as conduit for flow of information both out to the medical community and into the company:
- Development and execution of Global KOL medical engagement strategy
- Provide Neurology KOL engagement strategy
- Establish and/or enhance partnerships with key academic institutions and develop relationships with global key thought leaders
- Planning, designing and managing global medical Advisory Boards and gather insight from regional/local medical Advisory Boards
- Must have a MD, PhD or Pharm D level degree or equivalent
- Must have experience in Global or International Medical Affairs function (5+ years)
- Excellent communication skills both written and verbal.
- Experience/ability to work in a matrix cross-functional environment, both internally and remotely
- Excellent interpersonal skills with demonstrated track record and ability to drive results as an effective a team member and project leader
- Proven ability to manage budget and resources
- Strong business acumen
- Ability to build partnership access between HQ and affiliates
- Flexibility and ability to adapt to changing conditions
- Excellent problem solving, organizational, and negotiating skills
- Must demonstrate an energy and enthusiasm which brings a positive approach to all challenges Sense of ethics and responsibility
- Travel required up to 25%
- Scientific and technical acumen in Neurology and Neuro-immunology
- Understanding of Health Outcomes Research/Reiumbursment Experience
- Understanding of the global markets
Some opportunities happen only once in a lifetime – like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.
Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. As a leader in rare diseases for more than 25 years, Alexion has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D) as well as the first and only approved Factor Xa inhibitor reversal agent. In addition, the company is developing several mid-to-late-stage therapies, including a copper-binding agent for Wilson disease, an anti-neonatal Fc receptor (FcRn) antibody for rare Immunoglobulin G (IgG)-mediated diseases and an oral Factor D inhibitor as well as several early-stage therapies, including one for light chain (AL) amyloidosis, a second oral Factor D inhibitor and a third complement inhibitor. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, metabolic disorders and cardiology. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: www.alexion.com.